Sheen, who earns an estimated $1.8million per episode in his role as the star of the hit sitcom Two and a Half Men, joined Twitter on Monday and has already clocked up nearly 800,000 followers.
And with Sheen currently in the middle of a feud between the producers of Two and a Half Men following a radio interview, the comedy actor is sure to enjoy plenty of publicity in the coming weeks as he takes his outspoken views take to the Twittersphere.
Sheen joins a host of American celebrities on Twitter and Boylesports.com is 4/1 that Sheen overtakes Oprah Winfreyâ€™s 5.3m followers by the end of March.
The Scary Movie and Hot Shots! star is 7/1 to overtake the 6million currently following Katy Perry and 8/1 to have more followers than Ashton Kutcher (6.3million) by the end of the month.
Overtaking Barack Obama (6.8million) is likely to prove to be a tougher proposition at 14/1, whilst 18/1 is on offer for him to overtake Justin Bieberâ€™s 7.8 million followers and Lady Gagaâ€™s 8.5million fans.
The three-time divorced actor is also 2/1 to slate any of his ex-wives; Denise Richards, Donna Peele or Brooke Mueller and he is 9/4 to announce his engagement to Bree Olson or Natalie Kenly
â€œThereâ€™s no denying that Sheen is a colourful, controversial character and he is bound to come up with a controversial tweet at some point,â€ said Nicola McGeady, Boylesports PR Spokesperson.
â€œThe success of Two and a Half Men, his feud with the showâ€™s producers and his outspoken nature are sure to earn him a huge following â€“ but will it be enough to topple Gaga and Bieber?â€
Charlie Sheen Twitter Betting:
To have more followers by the end of March than:
Lady Gaga (8,513,963):Â 18/1 Justin Bieber (7,786,947): 18/1 Britney Spears (6,995,229): 16/1 Barack Obama (6,806,855): 14/1 Kim Kardashian (6,530,887): 10/1 Ashton Kutcher (6,390,721): 8/1 Ellen DeGeneres (6,039, 475): 7/1 Katy Perry (6,009,644):Â 7/1 Taylor Swift (5,460,742): 5/1 Oprah Winfrey (5,214,718): 4/1
To tweet about hisÂ 9/11 theories: 7/4 To slate any of his ex wives on twitter (Denise Richards, Donna Peele, Brooke Mueller): 2/1
To announce his engagement to Bree Olson or Natalie Kenly on twitter before the end of the year 9/4